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Blood-based and imaging biomarkers not only allow the identification of individuals at risk during prodromal stages but also provide measurable endpoints for clinical trials

A distinctive feature of HPAP is its multi-omics design, integrating snRNA-seq, snATAC-seq, whole-genome bisulfite sequencing (WGBS), morphometric techniques, and spatial technologies (Visium, CODEX)

Indeed, GDH1 knockdown reduced while exogenous -KG supplementation elevated intracellular -KG abundance (Extended Data Fig

Antioxidant enzyme activities and lipid oxidation in rape ( Brassica campestris L.) bee pollen added to salami during processing