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Remarkably, GH-responsive neurons are widely distributed across numerous brain areas, including the hippocampus, bed nucleus of the stria terminalis (BNST), amygdala, cerebral cortex, cerebellum, specific thalamic regions, and several brainstem nuclei (8, 9, 12)

The decrease in molecular oxygens valency due to electron loss leads to the formation of ROS (Watabe et al

For these reasons, the peptide is commonly included in anti-aging skin products [10, 11]

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