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The decrease in complex I activity drives an increase in glycolysis which in turn results in increased lactate production in intestinal epithelial cells and, in turn, increased Lac-Phe synthesis

FEBS Lett (2022) 596:80625

The Impact of Bariatric Surgery on Glutathione Synthesis in Individuals with Severe Obesity

Amycretin is a unimolecular dual agonist -- a single molecule that activates both GLP-1 and amylin receptors -- available in both injectable and oral formulations