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Interestingly, the location of neutrophils and macrophages coincided with the loss of alpha smooth muscle actin (aSMA) signal within the tunica media, indicating enhanced SMC loss at the site of inflammatory cell infiltration

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[11] In practice, sermorelin is almost never used during pregnancy, since treating chronic growth hormone deficiency can typically be deferred and other therapies (if needed) would be chosen if GH support was truly required