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We recently repurposed sertraline, an antidepressant that efficiently crosses the BBB, as a specific SHMT1/2 inhibitor with robust anti-cancer properties, effectively targeting ser/gly-dependent cancers in vitro and in vivo [33,34,35]

Along with other hormones, neurotransmitters, and genetic factors, melatonin is part of a complex chemical dance taking place every night, which can be easily disrupted and create the sleeping disorders seen so prevalently today

Characterisation of a cDNA encoding gamma-glutamylcysteine synthetase in Medicago truncatula