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In addition, the vaccine improved the physical activity of middle-aged mice (50 weeks old) and extended the median lifespan of ZMPSTE24 KO mouse (model of progeria), an extreme model of accelerated aging 62

it can be taken as a pill or under the tongueis when there is a deficiency that can be caused by pernicious anemia, celiac or Crohns disease, or weight loss procedures such as gastric bypass surgery, which interferes with the bodys ability to extract vitamins from food

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[3] Liposomal and sublingual forms are marketed as higher-bioavailability alternatives, though head-to-head data against standard oral tablets remain limited