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Uses of Diagnostic Tests for GERD Endoscopy Differentiate reflux esophagitis from other causes of esophagitis (eg, eosinophilic or infectious) Biopsy for Barrett esophagus or adenocarcinoma Dilate strictures Provide endoscopic therapy (if desired) Contrast radiography (not recommended for GERD diagnosis) Identify hiatal hernia Identify strictures Reproduce reflux of barium (not sensitive) Ambulatory 24-h pH studies Quantify acid reflux in the absence of esophagitis Determine temporal correlation between gastroesophageal reflux and atypical symptoms Abbreviation: GERD, gastroesophageal reflux disease

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