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Neurodegenerative diseases are characterized by progressive damage to functions of synapses, neurons, glial cells (Marchesi et al., 2021

Shpilka, T

This revealed 38 variants that were both identified in our screen and characterized in the database as non-functional, damaging mutations (Fig

These enzymes use glutathione to bind and neutralize toxic by-products, including reactive and oxidative compounds generated during alcohol metabolism