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In some embodiments, administration of a formulation or composition or device described herein, in conjunction with otic surgery, medical device implantation, and/or cell transplantation, reduces or prevents cell damage and/or death (e.g., auris sensory hair cell death and/or damage) associated with otic surgery, medical device implantation, and/or cell transplantation

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Safety in Context: Study Limitations While the clinical trial safety data for AOD-9604 is extensive and reassuring, understanding the limitations of this evidence base is essential for balanced interpretation

Another key reason why NAC has gained so much attention is that it is the most direct precursor of glutathione , a tripeptide composed of cysteine , glycine and glutamic acid (15)