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Nutrition (2022) 103-104:111840

In tissue repair models, angiogenesis is important because damaged tissue needs a functional vascular response for oxygen delivery, nutrient movement and repair signalling

In this study we have shown how a purine nucleoside triphosphate, Guanosine triphosphate (GTP), binding establishes rigidity-based allosteric communication with the regulatory coenzyme NADH and then synergistically inhibits the oxidative deamination activity of mammalian GDH by stabilizing its closed conformation