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Moreover, ROS exerts an important effect on microglia as the second messenger, modifying inflammatory gene transcription and, consequently, amplifying the inflammation

As many of these transmembrane receptors are dimerized or heterodimerized by the interaction with cognate ligands to activate signalling pathways 1,38 , the methodology reported here is applicable to the design and synthesis of such artificial agonists

COX2 regulates senescence secretome composition and senescence surveillance through PGE(2)

Healthcare consumption decreases in parallel with improvements in quality of life during GH replacement in hypopituitary adults with GH deficiency