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Beta-3 adrenergic receptors can desensitise under chronic agonist exposure, a phenomenon documented in the context of other beta-adrenergic agonists

I kept campaigning for a move, as it became obvious to me that the altitude wasnt working well for my husband (and also, the altitude seemed to affect our sons sleep as well, so that meant none of us were sleeping), and he finally agreed to a trial of being in LA for at least three months in December of 2020