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While animal studies show promising results for tendon, muscle, and ligament repair, there are zero controlled human safety trials, and research suggests 12% to 58% of peptide products are contaminated, which is why the FDA classifies it as Category 2, and it's banned by WADA, NCAA, NFL, NBA, MLB, NHL, UFC, and PGA

The onset of conditions like Polioencephalomalacia (Goat Polio) can disrupt thiamine production in the rumen, leading to metabolic slowdown, cell death, and brain swelling

The safest approach is to assume detection windows longer than published estimates

Factors such as age, changes in the gut, autoimmune conditions, or lifestyle choices like a vegetarian diet may contribute to this