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This marks yet another devastating, one-two money-losing punch to Cubas economy, where tourism and cigars are major sources of income for the beleaguered Communist nation

TABLE 1 Cytochromes involved in the metabolism of antidiabetic drugs and possible effects of tobacco smoke compounds on their metabolic activities

Another suggested ECS adverse effect is direct suppression on pulmonary epithelial cilia movement leading to impairment of clearance of toxic particles and increase the risk of respiratory infections [123]