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Drug Interactions: Certain medications, like metformin and stomach acid reducers (PPIs), can interfere with B12 absorption from food, which may increase the need for injections

and E.S.: data curation

doi: 10.1159/000488326 Summary Keywords Sucrosomial vitamin B12, Sucrosomial technology, vitamin B12 deficiency, oral B12 supplement, vitamin B12 bioavailability Citation Memon NM, Conti G, Brilli E, Tarantino G, Chaudhry MNA, Baloch A, Shafiq A, Mumtaz SU, Qaisar W, Iqtadar S, Abrar S, Kanwal A, Akhtar MH, Latif H, Rabbani F, Ujjan ID, Turroni S and Khan A (2024) Comparative bioavailability study of supplemental oral Sucrosomial vs

A simpler approach is to plan your starting dose and dose escalation so you finish the vial within 28 days