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NF-B: nuclear factor kappa-light-chain-enhancer of activated B cells

In this study, we show that isolated mitochondria exposed to colistin undergo rapid depolarization of the mitochondrial inner membrane, indicating that mitochondrial damage is likely to be an early event in colistin-induced kidney injury

Role of other factors on TRP channels and pain In addition to the oxidative stress, several other factors play a role in the induction of CIPN with/without TRP channel activation, including glutamate receptors, neuropeptides, PKC and inflammation

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