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Review of the midbrain ascending arousal network nuclei and implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM)

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Most stacking claims rest on mechanistic plausibility, individual-compound efficacy data in matched models, and the practical observation that the two compounds produce no obvious antagonism in co-administration

Embora os resultados especficos de cada combinao ainda sejam uma rea de investigao contnua, os dados pr-clnicos existentes apoiam a justificativa para estudar esses peptdeos em conjunto em sistemas experimentais controlados