A single freeze-thaw cycle can reduce bioactivity by 3040% in sensitive peptides
That dose, adjusted for human weight, would be roughly 1,600 mg for an average adult, far exceeding any practical use by orders of magnitude

Joseph Cold Tablets (for children), Stanback Analgesic, Stanback Powder, Sudafed, Sulindac Tablets, Supac, Surmontin, Surmontil, Synalogos Capsules, Synalgos-DC Capsules T Talwin Compound, Tenol-Plus, Tenuate Dospan, Theracin, Thorazine, Ticlid, Ticlopidine, Tolectin 200,600 Tablets, Tolectin DS Capsules, Tolmetin Tablets/Capsules, Toradol Injection/Tablets, Tr-Pain Tablets, Tri-Pain, Trental, Triavil, Tricosal tablets, Trigesic, Trigestic, Trilisate, Trilisate Tablets and Liquid, Tusal U Ultrapin, Unipro, Ursinis, Ursinos Inlay Tablets V Valerian, Valesin, Valtrex, Vanquish, Verin, Vibramycin, Vicoprofen, Vioxx, Viro- Med Tablets, Visken, Vitamin-E, Vivactil, Vivarin, Voltaren W Warfarin (Coumadin), Wellbutrin, Wesprin Buffered Y Yohimbe Z Zactrin, Zoloft (Zoloft has anti-coagulant properties so just advise your anesthesiologist if you take it) Zorprin, Zyban *Also a diet low in sodium is beneficial before and after any surgery

Figure 8 illustrates various mechanical approaches of transdermal delivery including microneedle arrays