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3.4 ABC transporter family Another tamoxifen target are proteins responsible for chemotherapeutic efflux of antitumor agents, this action is responsible for multidrug resistance mechanism in cancer patients (MDR)

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doi:10.1074/jbc.M109.067017, PMID: 20498365 Tavazzi B, Amorini AM, Fazzina G, Di Pierro D, Tuttobene M, Giardina B, Lazzarino G (2001) Oxidative stress induces impairment of human erythrocyte energy metabolism through the oxygen radical-mediated direct activation of AMP-deaminase

Inoue K, Yuasa H (2013): Molecular basis for pharmacokinetics and pharmacodynamics of methotrexate in rheumatoid arthritis therapy