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Marchetti P, Decaudin D, Macho A, Zamzami N, Hirsch T, Susin SA et al

Introduction of the amplitude modulation (AM) mode (also known as tapping mode) in 1993, where the cantilever is oscillated in the Z-direction at (or near) resonant frequency, and this oscillation amplitude is measured to detect the tip-sample interaction, facilitated the observation of biomolecular processes allowing analysis of molecules weakly attached to a substrate surface (Zhong et al., 1993)

A few years after publishing their data, the same researchers repeated their experiments

B12 is internal nutrient support, not a cosmetic treatment, so a before-and-after image would misrepresent what it does