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Fig 1: Vitiligo disease During the process of wound healing, reduced expression of the adhesion molecule E-cadherin is thought to promote the movement of melanocytes

It takes part in the reduction of tocopheroloxyl radical (TocO) to -tocopherol with the appearance of an ascorbate radical (semidehydroascorbate): + + The ascorbate radical (A), in turn, is reduced to ascorbate (AN) with the help of reduced glutathione and the enzyme glutaredoxin: + 2GSH AH- + CSSG + + , as well as NADH-dependent semidihydroascorbine reductase: + NADH AH- + D+, and NADPH-dependent thioredoxin-reductase: + NADP AH- + NADP+ Reduced glutathione

that's three steps with a little lost at each one