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A: Rather than broadly inhibiting all MMPs, GHK-Cu research has documented selective effects: inhibitory activity toward MMP-1 (which degrades structural collagen) while stimulating MMP-9 (which facilitates cell migration and matrix clearing)

Compared with the COPD rats treated with NAC + oe-VWF + sh-NC, levels of IL-6 and TNF- elevated in serum of COPD rats treated with NAC + oe-VWF + sh-p38 MAPK (Fig