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GH and testosterone have well-documented additive effects on body composition testosterone drives muscle protein synthesis through androgen receptor activation, while GH promotes lipolysis, collagen synthesis, and tissue repair through separate pathways

376 While detailed spectroscopic studies have led to atomic-level models of the different holo RcnR species that define residues beyond the W-X-Y-Z motif, the lack of a structure hinders our understanding of the allosteric mechanism of transcriptional derepression by RcnR

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