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doi: 10.1186/1475-2840-9-31 46 TassoneEJSciacquaAAndreozziFPrestaIPerticoneMCarnevaleDet al

The indicated proteins harbour phosphosites that are unaffected in insulin resistance, emergent in insulin resistance (Fazakerley et al

In this regard, a key mode of action to explain this relationship is via glucose transporter type 1 (GLUT1) which increases uptake of the oxidized form of ascorbic acid, dehydroascorbate and subsequently depletes glutathione (Yun et al., 2015)

Additionally, another study used plasma exosomes to deliver siRNA to T cells and monocytes and caused post-transcriptional gene silencing in recipient cells