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Activated mTORC1 phosphorylates its downstream targets S6 kinase 1 (S6K1) and the eIF4E binding protein 1 (4E-BP1) to regulate protein synthesis [36]

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Its use is based on individual health factors and provider judgment

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A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease

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