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[1] BPC -57 is a penta-decapeptide made up of 15 amino acids, and is derived from a stretch of endogenous BPC identified and isolated from gastric juice
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In our study, NAC co-treatment not only ameliorated the impaired performance in NOR, Y maze, and MWM in chronic ethanol-exposed APP/PS1 mice, but also significantly alleviated the neuroinflammation, downregulated TNF- protein level and restored SYP, PSD95 and BDNF protein levels in the hippocampus of ethanol-exposed APP/PS1 mice, further suggesting the critical role of chronic ethanol exposure mediated oxidative stress and neuroinflammatory damage in AD pathology and the cognitive behavioral impairments
For cholangiocyte organoid infection, duct cells (passage 0 or 1) were extracted from Matrigel and digested with TrypLE to prepare single-cell suspensions as described in ref
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