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In addition to its pro-differentiating actions, nicotinamide promotes neuronal survival, especially in oxidative stress environments, through various pathways, such as maintenance of protein kinase B (akt)-dependent phosphorylation of forkhead transcription factor (FOXO3a)

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The effects of serotonin dysregulation include significant mental and physical health impacts due to serotonins important role in mood, cognitive functions, and overall well-being