That single fractionation study is the proof point researchers still cite more than fifty years later as the origin of the entire copper-peptide research field: a compound identified almost by accident in a liver-aging comparison went on to become one of the most studied metallopeptides in dermal and regenerative research
4 Fatty acids Fatty acids can be divided into saturated fatty acids (SFA), mainly from dairy products and meat, monounsaturated fatty acids, mainly from sunflower oil, peanut oil, olive oil, and polyunsaturated fatty acids, mainly from vegetable oils, fish oil, and marine animals, according to the saturation degree
The copper complex itself is not optional decoration: the copper ion is what activates the receptor signaling at fibroblast surfaces
Cell Immunol 140:3909 Robinson MK, Roderick ML, Jacobs DO, Rounds JD, Collins KH, Saporoschetz IB, Mannick JA, Wilmore DW (1993) Glutathione depletion in rats impairs T-cell and macrophage immune function