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Chronic smoke exposure increased the number of dead cells, lactate dehydrogenase release, and interleukin-8 (IL-8) secretion and decreased apical cilia, cystic fibrosis transmembrane conductance regulator (CFTR) protein levels, and transepithelial resistance

Little is known about the health effects of e-cigarettes, which many users pick up as a less dangerous alternative to smoking, but the nicotine they contain is widely considered harmful to adolescent brain development

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