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Additionally, it has been recommended that patients having elective procedures consume only clear fluids for 24 hours before surgery

Takeda T, Azumi J, Masaki M, Nagasawa T, Shimada Y, Aso H, et al

This level of precision is overkill for standard dosing but invaluable for microdosing protocols where researchers work with doses of 0.25 mg to 1 mg

Taking your GLP-1 injection at the same time every week (or every day, for daily formulations) matters more than choosing the theoretically perfect hour