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Acute inactivation of the VHL gene contributes to protective effects of ischemic preconditioning in the mouse kidney

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Furthermore, elevation in ELF GSH levels was not arbitrary since the CS induced GSH adaptive response after a 3d exposure period prevented GSH levels from dropping below basal levels

Because if you randomize diabetics to something like old-fashioned bloodletting, but instead of leeches, they just donate blood a couple times to lower their iron stores, and those in the blood donation group had better blood sugar control, better insulin secretion, and less insulin resistance