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Applying products with high-strength vitamin C (L-ascorbic acid) or directly combining them with acids (like almost any AHAs/BHAs) is counterproductive, says Shamban, because the low pH of these acids can degrade the peptides, reducing their efficacy

Zhu X, Zhao X, Zhang J, Zhang Y, Dong X, Hou Y, Jia Z, Zhang Y, Gao W (2025) BaziBushen inhibition of oocyte ferroptosis in primordial follicles through activation of NF2-YAP pathway for the treatment of chemotherapy-induced premature ovarian insufficiency