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When your body doesnt have enough vitamin B12, myelin is produced differently and your nervous system functions improperly

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In diseases resulting in large bile duct obstruction, extrahepatic and intrahepatic biliary dilatation can be identified on imaging studies, especially if the bilirubin concentration is more than 10 mg/dL and the patient has had jaundice for more than 2 weeks

Because it has a short half-life, daily administration is common in literature to keep the IRR activated periodically