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Hypertension 37(2):194198 Halimi JM, Giraudeau B, Vol S et al (2002) The risk of hypertension in men: direct and indirect effects of chronic smoking

Acute inflammation, including from hypersensitivity to the chemicals found in flavored e-juice, can result in difficulty breathing, scarring of the lungs, and even respiratory failure

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Collectively these findings in humans, animals, and cells strongly support the need to investigate the effects of ENDS aerosol exposures on asthmatic responses, with a particular focus on MMP12 involvement in a combined ENDS + HDM-induced asthma model