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However, while one study reported an antidepressant effect of AA mediated by the L-argininenitric oxideserotonergic system, its anti-inflammatory and anti-ferroptotic effects have not been investigated in the context of depression (Jnior et al., 2019)

The peptide has been studied extensively across various organ systems, demonstrating cytoprotective effects in the gastrointestinal tract, liver, pancreas, heart, blood vessels, muscle, tendon, ligament, bone, and nervous system

Paraspinal muscle pathophysiology associated with low back pain and spine degenerative disorders

Its role appears modulatory rather than suppressive, supporting coordinated neural and endocrine timing rather than inducing forced sleep states