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[13] The researchers also noted that The results also demonstrate that the degeneration of OA cartilage may be delayed by MGF [exposure] partially via unfolded protein response regulated by protein kinase RNA-like endoplasmic reticulum kinase. PEG-MGF and Dental Activity Periodontal ligament cell culture studies indicate that the pegylated peptide may improve osteogenic differentiation and potentially enhance MMP-1 and MMP-2 expression

doi: 10.1016/j.abb.2006.11.021

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