David Sinclair: That was reversible very easily, just in a few weeks, a couple weeks even, so I dont yet think theres a limit, well see of course, but given that result I am optimistic that were not just talking about helping fresh wounds or wounds that are not wounds, but diseases that have just begun
CRT/DRE, C-repeat and dehydration-responsive element
In some embodiments, Sodium Thiosulfate, Potassium Thiosulfate, HMTBa, Oltipraz, D-cysteine, D-methionine, or a combination thereof improves hair cell survival, function, viability, health, growth, or a combination thereof following chemotherapy-induced ototoxicity by at least or about 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or more than 95%
Only nonselective agents should be used rather than 1-selective agents (eg, metoprolol)