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Animal numbers were chosen with consideration of ethical requirements and the 3Rs principle (replacement, reduction, refinement) to balance statistical sensitivity with minimizing animal use 18

How long do I need B12 injections after damage from nitrous oxide

Vitamin B12, or cobalamin, is essential for many key functions in the body

Despite these challenges, IN delivery is predominantly used for emergency medicine in clinical settings due to its rapid onset, ease of administration, and ability to bypass hepatic first-pass metabolism