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Subsequently, whole exome sequencing (WES) of simplex families with one affected child demonstrated strong association of rare de novo exonic single nucleotide variants (SNV) with ASD [20,21,22,23,24], with more recent analyses highlighting around a hundred genome-wide significant ASD risk genes [25, 26]

Circ Res 54(6):694702 Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA (1987) Human cardiac myosin heavy chain genes and their linkage in the genome

The long-term significance of these observations is unknown

Wu X, Jia Q, Ji S et al (2020) Gamma-aminobutyric acid (GABA) alleviates salt damage in tomato by modulating Na + uptake, the GAD gene, amino acid synthesis and reactive oxygen species metabolism