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Indeed, in a retrospective study, administration of anti-tumor necrosis factor (anti-TNF) to clinically diagnosed IBD patients led to a 78% reduction in the risk of developing PD, compared to untreated controls (Peter et al., 2018)

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In other embodiments, the delivery system comprises multiple syringes, each syringe of the multiple syringes contains at least one component of the formulation such that each component is pre-mixed prior to injection or is mixed subsequent to injection