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And the consequences of that impulse can be seen in Massachusetts, which has prohibited sales of flavored tobacco or vaping products since 2019, stimulating sales in neighboring states, black-market activity, and criminal prosecutions

For varenicline-treated participants: 240 participants started treatment (177 in the control group plus 63 in the genetic group), 103 stopped smoking by Week 4 (5 relapsed before the end of the study), and 25 participants discontinued treatment

Theyve also been linked to various health effects, from increased heart rate and blood pressure to oral lesions and gum disease

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